Hyponatremia negatively affects outcome of patients with ST elevation myocardial infarction treated with primary angioplasty ...

Document Type : Full Length research Papers

Authors

1 cardiology, faculty of medicine, Fayoum university, Fayoum, Egypt

2 cardiology department, faculty of medicine , Fayoum university , Fayoum, Egypt

3 Cardiovascular medicine department – Fayoum University- Fayoum- Egypt

4 physiology department, faculty of medicine , Fayoum university , Fayoum, Egypt

5 cardiology department, faculty of medicine , Fayoum university, Fayoum , Egypt

Abstract

Serious health consequences such as increased mortality, morbidity, and longer hospital admissions are linked to hyponatremia. Cardiovascular mortality is correlated with hyponatremia in individuals with HF. Myocardial infarction may lead to hyponatremia due to the stimulation of the renin-angiotensin system and elevated production of catecholamines. The research objected to evaluate of the influence of hyponatremia on results in cases with ST segment elevation myocardial infarction handled by 1ry angioplasty during hospitalization and thirty days following discharge.The research involved one hundred cases (sixty-five cases with hyponatremia and thirty-five cases with normal sodium) hospitalized with STEMI and treated by primary angioplasty .The following were done for all cases: ECG, cardiac biomarkers, admission sodium level, and glomerular filtration rate (GFR). The intervention involved the use of stents and glycoprotein IIb/IIIa inhibitors during coronary angiography. In-hospital problems like mechanical complications, heart failure, arrhythmia and cardiac arrest and follow up for thirty days following discharge. we found that hyponatremia was associated with lower left ventricular Ejection fraction and Hyponatremia was more frequent in HF cases compared to in non-HF cases in the ICU33% of individuals suffered problems within 30 days. Complications occurred in 19% of cases with HF, 10% with re-infarction, and 2% with death or VT.

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