Impact of Acute Unilateral Anterior Ischemic Optic Neuropathy on Central Macular Thickness and Foveal Avascular Zone: An Optical Coherence Tomography and Angiography Study

Document Type : Full Length research Papers

Authors

1 Fayoum Ophthalmology Hospital, Fayoum, Egypt

2 Ophthalmology department fayoum university

3 Ophthalmology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt.

4 Department of Ophthalmology, Faculty of Medicine, Fayoum University, Fayoum, Egypt

10.21608/fumj.2025.315910.1386

Abstract

Introduction: Non-arteritic anterior ischemic optic neuropathy (NAION) is a known ischemic change that affects the optic disc. Fundus fluorescein angiography and visual field perimetry are useful in diagnosis of NAION. Optical coherence tomography (OCT) and Optical coherence tomography angiography (OCTA) are advanced non-invasive modalities that can be used for assessment of structural and vascular changes at different retinal levels.
Aim of the study: Aim of the study was to assess the impact of acute NAION on central macular thickness and foveal avascular zone using OCT and OCTA during acute phase (1-3 weeks from onset) before resolution of disc edema.
Subjects and Methods: This study included 30 patients diagnosed with unilateral acute NAION attending at Ophthalmology outpatient clinic in Fayoum University Hospitals. OCT and OCTA were done for all subjects (diseased and normal eyes) using Optovue, Inc., Fremont, CA, USA.
Results: showed a significantly lower CMT in diseased eyes after resolution of edema. Reduction in FAZ was statistically non-significant.
Conclusions: We can take into consideration the quantitative differences in
CMT during follow-up of the progression in NAION cases.
Keywords: “OCTA; neuropathy; macular; foveal”.

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Fayoum University Medical Journal
Volume 14, Issue 3
Surgical sub-specialties
March 2025
Pages 120-128

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