EFFECT OF VITAMIN D DEFICIENCY ON HYPERTROPHIC SCARRING: A meta-analysis.

Document Type : Review Articles

Author

dermatology at fayoum university

Abstract

Background: : Vitamin D is a fat soluable vitamin which is vital for different systems of the human body including endocrine and immune systems, endothelial function and wound healing.
Patients and methods: This meta-analysis follows the PRISMA flow diagram. The study asses the relationship between vitamin D deficiency and hypertrophic scar incidence and determine vitamin D replacement therapy effect on hypertrophic scar width and scale in patients who have deficiency in vitamin D.
Result: After the search and screening, one study was eligible for our meta-analysis. Results of meta-analysis shows that scar improvement occurred significantly with p value < 0.05 after vitamin D replacement in group (1) and this was represented by low level of Vancouver score but scar width did not change after treatment in both study groups.
Conclusion: Our study may provide evidence that Vitamin D supplement may be used like an adjuvent treatment for hypertrophic scars as it reduce vascularity, pliability, pigmentation, and height of scars with little effect on scar width.
Keywords: Vitamin D – hypertrophic scarring.

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Fayoum University Medical Journal
Volume 13, Issue 2
Medical Subspecialty
April 2024
Pages 76-85

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