Abstract Introduction: Due to iron overload, patients with beta-thalassemia may experience complications. Several adipokines have been proposed as potential contributors to the development of beta-thalassemia complications. One of the adipokines, fatty acid-binding protein 4 (FABP4), connects various elements of the inflammatory and metabolic pathways. Aim of the study: This study assessed B-thalassemia patients' serum (FABP4) levels and linked them to complications related to thalassemia. Subjects and Methods: There were fifty adult participants in this cross-sectional study. A thorough clinical examination and medical history were completed. Every participant had their serum levels of fatty acid binding protein four measured. Results: According to our findings, 24% of patients had HCV +ve, 36% had gall bladder stones, and 44% had elevated liver enzymes. Patients with serum ferritin levels greater than 2500 ng/ml and FABP4 level did not significantly correlate (p value < 0.05). Conclusions: Patients with beta thalassemia had elevated liver enzymes, GB stones, and a high prevalence of HCV +ve. There was no discernible relationship between patients with serum ferritin levels higher than 2500 ng/ml and FABP4 level. Keywords: FABP4, beta-thalassemia, complications.
Mohamed, B. (2024). Study of Fatty Acid Binding Protein 4 (FABP4) levels in Patients with Beta-thalassemia and its Related Complications.... Fayoum University Medical Journal, 13(2), 42-48. doi: 10.21608/fumj.2024.258395.1301
MLA
Basma Atiya Mohamed. "Study of Fatty Acid Binding Protein 4 (FABP4) levels in Patients with Beta-thalassemia and its Related Complications...". Fayoum University Medical Journal, 13, 2, 2024, 42-48. doi: 10.21608/fumj.2024.258395.1301
HARVARD
Mohamed, B. (2024). 'Study of Fatty Acid Binding Protein 4 (FABP4) levels in Patients with Beta-thalassemia and its Related Complications...', Fayoum University Medical Journal, 13(2), pp. 42-48. doi: 10.21608/fumj.2024.258395.1301
VANCOUVER
Mohamed, B. Study of Fatty Acid Binding Protein 4 (FABP4) levels in Patients with Beta-thalassemia and its Related Complications.... Fayoum University Medical Journal, 2024; 13(2): 42-48. doi: 10.21608/fumj.2024.258395.1301