Optical Coherence Tomography based criteria for evaluation of Choriodal Neovascularization

Authors

1 Professor of Ophthalmology and Head of ophthalmology department Faculty of Medicine – Fayoum University

2 Lecturer of Ophthalmology Faculty of Medicine – Fayoum University

3 Department of ophthalmology Faculty of Medicine – Fayoum University

Abstract

Purpose: To detect the role of optical coherence tomography in evaluation of Choriodal neovascularization in response to treatment with anti vascular endothelial growth factors (VEGF). Methods: A total of 30 eyes with treatment-naïve
choriodal neovascular membrane were examined using the OCT system before treatment and after treatment with anti
VEGF. Results: In treatment‐naïve CNV, The activity of CNV had been evaluated according to structural OCT by presence of Cystoid Macular Edema (CME), Subretinal Fluid (SRF) , Fibrovascular Pigment Epithelial Detachment (FPED) and macular thickening . There is gradual decrease in CMT along the treatment course with repeated intravitreal anti-VEGF
injections. 50 % of CNV patients had CME at baseline which gradually decreased with repeated anti-VEFG injections and disappeared completely after the third dose, 35 % of CNV patients had SRF at baseline which gradually decreased with repeated antiVEFG injections and disappeared completely after the third dose, Only two patients had PED before treatment, which gradually decreased along the course of treatment by three doses of anti VEGF injections. Conclusion:
OCT is an important modality of investigation for diagnosis of CNV and detecting activity and response with treatment with anti VEGF.
 

Keywords

Fayoum University Medical Journal
Volume 1, Issue 2
December 2018
Pages 36-41

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